Home > Terms > English, UK (UE) > pethidine
pethidine
Pethidine is indicated for the treatment of moderate to severe pain, and is delivered as a hydrochloride salt in tablets, as a syrup, or by intramuscular, subcutaneous or intravenous injection. For much of the 20th century, pethidine was the opioid of choice for many physicians; in 1975 60% of doctors prescribed it for acute pain and 22% for chronic severe pain. Compared with morphine, pethidine was thought to be safer, carry a lower risk of addiction and to be superior in treating the pain associated with biliary spasm or renal colic due to its putative anticholinergic effects. It was later discovered that these were all myths and that it carried an at least equal risk of addiction, possessed no advantageous effects on biliary spasm or renal colic compared to other opioids and that, due to its toxic metabolite, norpethidine, it was more toxic than other opioids, especially during long-term use.
- Part of Speech: noun
- Synonym(s):
- Blossary: Illegal Drugs
- Industry/Domain: Law enforcement
- Category: Drug trafficking
- Company:
- Product:
- Acronym-Abbreviation:
Other Languages:
Member comments
Terms in the News
Featured Terms
Nissan Esflow
Nissan's latest battery-powered concept sports vehicle that is able to accelerate from to 60 mph in 4 seconds. Reminiscent of Nissan's iconic 370Z, ...
Contributor
Featured blossaries
marija.horvat
0
Terms
21
Blossaries
2
Followers
The worst epidemics in history
Browers Terms By Category
- Air conditioners(327)
- Water heaters(114)
- Washing machines & dryers(69)
- Vacuum cleaners(64)
- Coffee makers(41)
- Cooking appliances(5)
Household appliances(624) Terms
- Wine bottles(1)
- Soft drink bottles(1)
- Beer bottles(1)
Glass packaging(3) Terms
- Mapping science(4042)
- Soil science(1654)
- Physical oceanography(1561)
- Geology(1407)
- Seismology(488)
- Remote sensing(446)
Earth science(10026) Terms
- Plastic injection molding(392)
- Industrial manufacturing(279)
- Paper production(220)
- Fiberglass(171)
- Contract manufacturing(108)
- Glass(45)
Manufacturing(1257) Terms
- Biochemistry(4818)
- Molecular biology(4701)
- Microbiology(1476)
- Ecology(1425)
- Toxicology(1415)
- Cell biology(1236)